2017
Figure 1. Identification of RLTPR (p.Q575E) as a Putative Gain-of-function Mutation in T Cell Lymphomas.
- Haugh AM, Zhang B, Quan VL, Garfield EM, Bubley JA, Kudalkar E, Verzi AE, Walton K, Vandenboom T, Merkel EA, Lee CY, Tan T, Isales MC, Kong BY, Wenzel AT, Bunick CG, Choi J, Sosman J, Gerami P. Distinct Patterns of Acral Melanoma Based on Site and Relative Sun Exposure. J Invest Dermatol. 2017 Sep 1. PMID: 28870692.
- Gmyrek GB, Pingel J, Choi J**, Green JM. Functional analysis of acquired CD28 mutations identified in cutaneous T cell lymphoma. Cell Immunol. 2017 Jul 10. PMID:28711152. ** co-corresponding author
- Park J, Yang J, Wenzel AT, Ramachandran A, Lee WJ, Daniels JC, Kim J, Martinez-Escala E, Amankulor N, Pro B, Guitart J, Mendillo ML, Savas JN, Boggon TJ, Choi J. Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E). Blood. 2017 Jul 10. PMID:28694326.
- Martinez-Escala ME, Kantor RW, Cices A, Zhou XA, Kaplan JB, Pro B, Choi J, Guitart J. CD8+ mycosis fungoides: A low-grade lymphoproliferative disorder. J Am Acad Dermatol. 2017 Jul 1. PMID:28676328.
- Zhou XA, Choi J. Photopheresis: Advances and Use in Systemic Sclerosis. Curr Rheumatol Rep. 2017 Jun;19(6):31. PMID:28466383.
2016
Figure 2. Identification of a Novel STAT3 Mutation in the Lymphocytic Variant of Hypereosinophilic Syndrome.
- King B, Lee AI, Choi J. Treatment of Hypereosinophilic Syndrome with Cutaneous Involvement with the JAK Inhibitors Tofacitinib and Ruxolitinib. J Invest Dermatol. 2016 Nov 22. PMID: 27887955.
- Weed J, Gibson J, Lewis J, Carlson K, Foss F, Choi J, Li P, Girardi M. FISH Panel for Leukemic CTCL. J Invest Dermatol. 2016 Nov 8. PMID: 27836797.
- Damsky WE, Choi J. Genetics of Cutaneous T Cell Lymphoma: From Bench to Bedside. Curr Treat Options Oncol. 2016 Jul;17(7):33. doi: 10.1007/s11864-016-0410-8. Review. PubMed PMID: 27262707.
- Pinzaru AM, Hom RA, Beal A, Phillips AF, Ni E, Cardozo T, Nair N, Choi J, Wuttke DS, Sfeir A, Denchi EL. Telomere Replication Stress Induced by POT1 Inactivation Accelerates Tumorigenesis. Cell Rep. 2016 Jun 7;15(10):2170-84. doi: 10.1016/j.celrep.2016.05.008. Epub 2016 May 26. PubMed PMID: 27239034.
- Yélamos O, Merkel EA, Sholl LM, Zhang B, Amin SM, Lee CY, Guitart GE, Yang J, Wenzel AT, Bunick CG, Yazdan P, Choi J, Gerami P. Non-overlapping Clinical and Mutational Patterns in Melanomas from the Female Genital Tract and Atypical Genital Nevi.J Invest Dermatol. 2016 May 21. pii: S0022-202X(16)31256-8. doi: 10.1016/j.jid.2016.05.094. [Epub ahead of print] PubMed PMID: 27220476.
- Gibson JF, Huang J, Liu KJ, Carlson KR, Foss F, Choi J, Edelson R, Hussong JW, Mohl R, Hill S, Girardi M. Cutaneous T-cell lymphoma (CTCL): Current practices in blood assessment and the utility of T-cell receptor (TCR)-Vβ chain restriction. J Am Acad Dermatol. 2016 May;74(5):870-7. doi: 10.1016/j.jaad.2015.12.018. Epub 2016 Feb 10. PubMed PMID: 26874819; PubMed Central PMCID: PMC4835257.
- Zhang X, Rao A, Sette P, Deibert C, Pomerantz A, Kim WJ, Kohanbash G, Chang Y, Park Y, Engh J, Choi J, Chan T, Okada H, Lotze M, Grandi P, Amankulor N. IDH mutant gliomas escape natural killer cell immune surveillance by downregulation of NKG2D ligand expression. Neuro Oncol. 2016 Apr 25. pii: now061. [Epub ahead of print] PubMed PMID: 27116977.
- Damsky WE, Craiglow BG, Choi J. A Discordant Cutaneous Eruption in a Neonatal Twin. JAMA Dermatol. 2016 Apr 1;152(4):463-4. doi: 10.1001/jamadermatol.2015.5050. PubMed PMID: 26791600.
- Ziai J, Matloff E, Choi J, Kombo N, Materin M, Bale AE. Defining the polyposis/colorectal cancer phenotype associated with the Ashkenazi GREM1 duplication: counselling and management recommendations. Genet Res (Camb). 2016 Mar 7;98:e5. doi: 10.1017/S0016672316000021. PubMed PMID: 26947005
- Bi M, Zhao S, Said JW, Merino MJ, Adeniran AJ, Xie Z, Nawaf CB, Choi J, Belldegrun AS, Pantuck AJ, Kluger HM, Bilgüvar K, Lifton RP, Shuch B. Genomic characterization of sarcomatoid transformation in clear cell renal cell carcinoma. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2170-5. doi: 10.1073/pnas.1525735113. Epub 2016 Feb 10. PubMed PMID: 26864202; PubMed Central PMCID: PMC4776463.
- Walker S, Wang C, Walradt T, Hong BS, Tanner JR, Levinsohn JL, Goh G, Subtil A, Lessin SR, Heymann WR, Vonderheid EC, King BA, Lifton RP, Choi J. Identification of a gain-of-function STAT3 mutation (p.Y640F) in lymphocytic variant hypereosinophilic syndrome. Blood. 2016 Feb 18;127(7):948-51. doi: 10.1182/blood-2015-06-654277. Epub 2015 Dec 23. PubMed PMID: 26702067; PubMed Central PMCID: PMC4760095.
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Goh G, Walradt T, Markarov V, Blom A, Riaz N, Doumani R, Stafstrom K, Moshiri A, Yelistratova L, Levinsohn J, Chan TA, Nghiem P, Lifton RP, Choi J. Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy. Oncotarget. 2016 Jan 19;7(3):3403-15. doi: 10.18632/oncotarget.6494. PubMed PMID: 26655088; PubMed Central PMCID: PMC4823115.
2015
Figure 3. Identification of CD28 as a Putative Oncogene.
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Choi J, Goh G, Walradt T, Hong BS, Bunick CG, Chen K, Bjornson RD, Maman Y, Wang T, Tordoff J, Carlson K, Overton JD, Liu KJ, Lewis JM, Devine L, Barbarotta L, Foss FM, Subtil A, Vonderheid EC, Edelson RL, Schatz DG, Boggon TJ, Girardi M, Lifton RP. Genomic landscape of cutaneous T cell lymphoma. Nat Genet. 2015 Sep;47(9):1011-9. doi: 10.1038/ng.3356. Epub 2015 Jul 20. PubMed PMID: 26192916; PubMed Central PMCID: PMC4552614.
- Hosler GA, Davoli T, Mender I, Litzner B, Choi J, Kapur P, Shay JW, Wang RC. A primary melanoma and its asynchronous metastasis highlight the role of BRAF, CDKN2A, and TERT. J Cutan Pathol. 2015 Feb;42(2):108-17. doi: 10.1111/cup.12444. Epub 2014 Dec 11. PubMed PMID: 25407517; PubMed Central PMCID: PMC4470704.
2014
Figure 4. Development of a Novel PiggyBac Transposon for Genome-wide Forward Genetic Screens.
- Little AJ, Subtil A, Choi J. Rapidly enlarging nodular plaque on the leg. JAMA Dermatol. 2014 Oct;150(10):1107-8. doi: 10.1001/jamadermatol.2014.1045. PubMed PMID: 25133474.
- Futterleib JS, Feng H, Tigelaar RE, Choi J, Edelson RL. Activation of GILZ gene by photoactivated 8-methoxypsoralen: potential role of immunoregulatory dendritic cells in extracorporeal photochemotherapy. Transfus Apher Sci. 2014 Jun;50(3):379-87. doi: 10.1016/j.transci.2013.10.003. Epub 2013 Oct 24. PubMed PMID: 24215840; PubMed Central PMCID: PMC4002663.
- Choi J, Landrette SF, Wang T, Evans P, Bacchiocchi A, Bjornson R, Cheng E, Stiegler AL, Gathiaka S, Acevedo O, Boggon TJ, Krauthammer M, Halaban R, Xu T. Identification of PLX4032-resistance mechanisms and implications for novel RAF inhibitors.Pigment Cell Melanoma Res. 2014 Mar;27(2):253-62. doi: 10.1111/pcmr.12197. Epub 2014 Jan 6. PubMed PMID: 24283590; PubMed Central PMCID: PMC4065135.
2011
- Ko CJ, Milstone LM, Choi J, McNiff JM. Pityriasis rubra pilaris: the clinical context of acantholysis and other histologic features. Int J Dermatol. 2011 Dec;50(12):1480-5. doi: 10.1111/j.1365-4632.2011.04990.x. PubMed PMID: 22097993.
2008
- Lansigan F, Choi J, Foss FM. Cutaneous T-cell lymphoma. Hematol Oncol Clin North Am. 2008 Oct;22(5):979-96, x. doi: 10.1016/j.hoc.2008.07.014. Review. PubMed PMID: 18954747.
2007
- Choi J, Foss F. Cutaneous T-cell lymphoma: Biologic targets for therapy. Curr Hematol Malig Rep. 2007 Oct;2(4):272-7. doi: 10.1007/s11899-007-0037-8. Review. PubMed PMID: 20425380.
2006
- Choi J, Foss F. Efficacy of low dose clofarabine in refractory precursor T- acute lymphoblastic leukemia. Yale J Biol Med. 2006 Dec;79(3-4):169-72. PubMed PMID: 17940627; PubMed Central PMCID: PMC1994805.
2005
- Choi J, Walker J, Talbert-Slagle K, Wright P, Pober JS, Alexander L. Endothelial cells promote human immunodeficiency virus replication in nondividing memory T cells via Nef-, Vpr-, and T-cell receptor-dependent activation of NFAT. J Virol. 2005 Sep;79(17):11194-204. PubMed PMID: 16103171; PubMed Central PMCID: PMC1193601.
- Choi J, Walker J, Boichuk S, Kirkiles-Smith N, Torpey N, Pober JS, Alexander L. Human endothelial cells enhance human immunodeficiency virus type 1 replication in CD4+ T cells in a Nef-dependent manner in vitro and in vivo. J Virol. 2005 Jan;79(1):264-76. PubMed PMID: 15596822; PubMed Central PMCID: PMC538695.
2004
- Choi J, Enis DR, Koh KP, Shiao SL, Pober JS. T lymphocyte-endothelial cell interactions. Annu Rev Immunol. 2004;22:683-709. Review. PubMed PMID: 15032593.
2003
- Madge LA, Li JH, Choi J, Pober JS. Inhibition of phosphatidylinositol 3-kinase sensitizes vascular endothelial cells to cytokine-initiated cathepsin-dependent apoptosis. J Biol Chem. 2003 Jun 6;278(23):21295-306. Epub 2003 Mar 27. PubMed PMID: 12663669.
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“Grit is passion and perseverance for very long-term goals. Grit is having stamina. Grit is sticking with your future, day-in, day-out. Not just for the week, not just for the month, but for years. And working really hard to make that future a reality. Grit is living life like it’s a marathon, not a sprint.”
–Angela Lee Duckworth, Grit